Nitromemantine[ edit ] The NMDA receptor is regulated via nitrosylation and aminoadamantane can be used as a target-directed shuttle to bring nitrogen oxide NO close to the site within the NMDA receptor where it can nitrosylate and regulate the ion channel conductivity. Unlike many other NO donors, alkyl nitrates do not have potential NO associated neurotoxic effects. Alkyl nitrates donate NO in the form of a nitro group as seen in figure 7, -NO2- which is a safe donor that avoids neurotoxicity.
Consciousness and the Pineal Gland The pineal gland has always held an elevated status in the records of most ancient cultures.
Each family of glands in the endocrine system secrete hormones that stimulate certain aspects of bodily function: The pineal gland secretes hormones that modulate the state of consciousness.
Melatonin functions on a daily basis, METAtonin is rarely, if ever, produced. Melatonin is easy to detect in the blood; METAtonin is not, for there is a scavenger in the blood that readily destroys it. Recently,several scientific discoveries have verified this suspicion.
Rodents and humans have a very similar cellular structure and that is why they are used for endocrine research. Pineal secreted METAtonin allows us to experience a dimension of human consciousness above the normal or default level of awareness. Upon birth, our self-consciousness is suddenly thrown into the physical world of the additional dimensions of space and time.
In this new dimension of consciousness, one is gifted with a toolbox of the 5 physical senses, the flow of time and the awareness of being a separate body.
As we grow, we become accustomed to the parameters of this body and also develop the instinctive bodyguard awareness of the ego. The pathway to this enhanced level of consciousness is available to all humans; it is hard-wired into our brain architecture, like a homing circuit, although it is rarely activated.
This dimension of illumination is accessed by special stimulation of the pineal gland which then formulates the secretion, METAtonin, whose main active ingredient, DMT allows one to enter this additional dimension of human consciousness or OBC, Out-of-Body Consciousness.
An event of this nature rarely occurs in the course of a lifetime - maybe only once, but when it does, it is not forgotten and in many cases it results in the development of a whole new perspective and direction in life.
The potential for internally produced DMT-based METAtonin to influence the circuitry of the brain has been an ever-present component of human existence and throughout history, the influence of its effect may have played a part in many of our greatest discoveries and epiphanies.
The pineal gland is so named due to its similarity in shape to the pinecone, a symbol that is used in many religious themes including the giant pine cone statue at the Vatican, originally from Egypt, and the pine cone at the top of the pope's staff and the cone atop Buddha's head.
Science has yet to confirm whether consciousness itself has a physical component, and though several experiments in this area have been made, none are conclusive. It is generally assumed that consciousness could not exist without the framework of the brain, but again, this has yet to be proven.
Discoveries in quantum and theoretical physics have further encouraged inquiry into the phenomenon of consciousness, for it appears to be one of the fundamental formative forces in the universe - perhaps the first, be sure to visit chapter five for further information.
Many award-winning physicists are now considering the primacy of consciousness: It has no lens, pupil or iris, but it does have a retina. In fact, the pineal gland may prove to be more like a television receiver. The contents of this research resource are derived mainly from observed scientific phenomena as well as some well-founded speculation.
We are attempting to provide the general public with the broad spectrum of information available regarding the pineal gland and its relationship with endogenous DMT. In some cases we have simplified scientific concepts to make them more understandable and we have used some sources that are not from the established scientific community but, in our opinion, worthy of consideration.
If you have experienced a profound Out-of-Body experience, be it a waking OBE, a Near-Death Experience or a Lucid Dream experience and are looking for an explanation, you have come to the right place. There are other possible explanations: We have been born to be curious. Why are we here?
Where are we from…and going to? Do we have a connection to our creators? We hope you find some answers here.
We will begin with a technical discussion of the consciousness portal chemical itself: As mentioned earlier, synthetically produced DMT when it is sold on the street is categorized as a class one controlled illegal substance.
It is suspected that METAtonin performs an essential psychological function during gestation, early childhood and during the death process and at times in the midst of our lives The name METAtonin is an attempt to differentiate these two:Nitrous oxide is a colorless, sweet-tasting gas.
It is also known as "laughing gas". Continued breathing of the vapors may impair the decision making process. Ang II and ionotropic glutamate receptors in spinal cord segments A significant upregulation of AT1 mRNA levels in T segment only ( * fold-change, n = 4, p.
The blood glutamate scavengers injection could be administered immediately after an accident without first confirming a diagnosis of spinal-cord injury. “Our takeaway is, ‘Don’t wait to diagnose it, treat it,'” Ruban said.
Type or paste a DOI name into the text box. Click Go. Your browser will take you to a Web page (URL) associated with that DOI name. Send questions or comments to doi. Anyone with an impairment of brain or neurological function – whether mental illness, depression, seizures, brain cancer, headaches, neuropathy, brain infections, or any other neurological condition – should try a ketogenic diet to see if it improves the condition.
Research for this paper was funded by Ontario Neurotrauma Foundation and Krembil Neuroscience Program Evaluation of the sodium-glutamate blocker riluzole in a preclinical model of cervical spinal.